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1 Avril: Todd Treangen (UMPC - ABI Paris) |
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Written by Pierre PETERLONGO
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On the detection and abundance of large repeats in prokaryote genomes
10h30 Salle Aurigny
De novo repeat detection tools help to bridge the widening gap between newly sequenced genomes and the repeats found in annotation databases. While there exist software tools for detecting pairwise repeats, software tools for direct construction of repeat families while allowing for substitutions and indels for accurate repeat boundary prediction are lacking. We thus propose a novel software tool called Repeatoire based on an efficient local multiple alignment heuristic that will be discussed. Using Repeatoire, we have recently conducted a survey of the abundance of repetitive DNA in nearly 700 prokaryote chromosomes by searching for all large repeats > 300 nt. Results of this study will be presented. |
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